BDBM14493 5-benzyl-6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethynyl}pyrimidin-4-amine::CHEMBL420879::alkynylpyrimidine 7

SMILES Nc1ncnc(C#Cc2ccc(nc2)N2CCOCC2)c1Cc1ccccc1

InChI Key InChIKey=ODPJCEINZKGFRL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14493   

TargetAdenosine kinase(Rat)
Abbott Laboratories

LigandPNGBDBM14493(5-benzyl-6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethy...)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:ADK activity was monitored by a radiochemical assay, which measures the conversion of radioactive Ado ([U-14C] adenosine or [2-3H] adenosine) to AMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2007
Entry Details Article
PubMed
TargetAdenosine kinase(Rat)
Abbott Laboratories

LigandPNGBDBM14493(5-benzyl-6-{2-[6-(morpholin-4-yl)pyridin-3-yl]ethy...)
Affinity DataIC50: 40nMAssay Description:Evaluated in vitro for inhibitory activity against Adenosine kinase (AK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed