BDBM144618 US8969586, 26::US9598436, 26

SMILES FC(F)(F)COc1ncncc1-c1cccc2c(noc12)-c1cnccn1

InChI Key InChIKey=KECLLAMWOPXTIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144618   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM144618(US8969586, 26 | US9598436, 26)
Affinity DataIC50: 65nMpH: 7.2 T: 2°CAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM144618(US8969586, 26 | US9598436, 26)
Affinity DataIC50: 65nMAssay Description:The assays were performed in U-bottom 384-well optiplates. The final assay volume was 15 μl prepared from 7.5 μl additions of microsomes (p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
Go to US Patent