BDBM144610 US8969583, 68

SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2nsc(NC(=O)NCCCN3CCCC3)c2C(N)=O)cc1

InChI Key InChIKey=RCHBURXYVZCGRM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 144610   

TargetVascular endothelial growth factor receptor 2(Human)
Allergan

US Patent
LigandPNGBDBM144610(US8969583, 68)
Affinity DataIC50: 10nMpH: 7.4 T: 2°CAssay Description:Biochemical KDR kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug/well of poly-Glu-Tyr (4:1) in 10 mM P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
Go to US Patent

TargetPlatelet-derived growth factor receptor beta(Human)
Allergan

US Patent
LigandPNGBDBM144610(US8969583, 68)
Affinity DataIC50: 12nMpH: 7.4 T: 2°CAssay Description:Biochemical PDGFRbeta kinase assays were performed in 96 well microtiter plates that were coated overnight with 75 ug of poly-Glu-Tyr (4:1) in 10 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
Go to US Patent