BDBM14447 2-quinolone analog 24::4-(3-chlorophenyl)-1-methyl-6-({5-[(4-oxo-1,4-dihydropyridin-1-yl)methyl]-1H-imidazol-1-yl}methyl)-1,2-dihydroquinolin-2-one

SMILES Cn1c2ccc(Cn3cncc3Cn3ccc(=O)cc3)cc2c(cc1=O)-c1cccc(Cl)c1

InChI Key InChIKey=IBAVHLSMEQFZPY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14447   

LigandPNGBDBM14447(4-(3-chlorophenyl)-1-methyl-6-({5-[(4-oxo-1,4-dihy...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
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Date in BDB:
3/26/2007
Entry Details Article
PubMed