BDBM14441 2-quinolone analog 26::4-{[5-({[4-(3-chlorophenyl)-1-methyl-2-oxo-1,2-dihydroquinolin-6-yl]methoxy}methyl)-1H-imidazol-1-yl]methyl}benzonitrile

SMILES Cn1c2ccc(COCc3cncn3Cc3ccc(cc3)C#N)cc2c(cc1=O)-c1cccc(Cl)c1

InChI Key InChIKey=AACXPWKKIIIIEL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14441   

LigandPNGBDBM14441(4-{[5-({[4-(3-chlorophenyl)-1-methyl-2-oxo-1,2-dih...)
Affinity DataIC50: 89nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed