BDBM14432 1-(3-chlorophenyl)-5-[(4-chlorophenyl)(hydroxy)(1-methyl-1H-imidazol-5-yl)methyl]-3-methyl-2,3-dihydro-1H-1,3-benzodiazol-2-one::benzimidazolone analog 8

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2n(-c3cccc(Cl)c3)c(=O)n(C)c2c1

InChI Key InChIKey=VIPSZHALINMHRX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14432   

LigandPNGBDBM14432(1-(3-chlorophenyl)-5-[(4-chlorophenyl)(hydroxy)(1-...)
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:The in vitro activity of compounds inhibiting FTase was determined by measuring the transfer of [3H]-FPP to substrate Ha-Ras-CVLS. The incorporated r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMed