BDBM143448 US9682953, 20.A-18

SMILES COc1ccccc1-n1nc2C(=O)N(c3ccc(F)c(Cl)c3)C(CC3CO3)(c2c1C(C)C)c1ccc(Cl)cc1

InChI Key InChIKey=XNCLZJTUDGKMCN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 143448   

TargetFatty-acid amide hydrolase 1(Human)
Advinus Therapeutics

US Patent
LigandPNGBDBM143448(US9682953, 20.A-18)
Affinity DataIC50: 4nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Advinus Therapeutics

US Patent
LigandPNGBDBM143448(US9682953, 20.A-18)
Affinity DataIC50: 35nMpH: 7.4 T: 2°CAssay Description:All reagents were purchased from Sigma-Aldrich unless specified. Human and Rat Fatty Acid Amide Hydrolase (FAAH) genes used in assay have been descri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2018
Entry Details
Go to US Patent