BDBM14335 2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chloro-6-phenylbenzen-1-olate::CRA-11111

SMILES NC(=[NH2+])c1ccc2[nH]c(cc2c1)-c1cc(Cl)cc(-c2ccccc2)c1[O-]

InChI Key InChIKey=QHOGUHKKMFDODA-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 14335   

TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  13nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Celera

LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  250nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Celera

LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  540nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  590nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetProthrombin(Human)
Celera

LigandPNGBDBM14335(2-{5-[amino(iminiumyl)methyl]-1H-indol-2-yl}-4-chl...)
Affinity DataKi:  1.00E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed