BDBM143268 US8940771, 80

SMILES CN(C)CCN(C)c1nccc(n1)-c1sc(NC(=O)N2CCC[C@@]2(C)C(N)=O)nc1C

InChI Key InChIKey=XGPOESSTWCMYPH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 143268   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis

US Patent

LigandBDBM143268(US8940771, 80)Copy SMILESCopy InChI

Affinity DataIC50: 250nMpH: 7.5Assay Description:Typically frozen cells from 10 L of Tn5 cell culture were resuspended in Lysis Buffer 20 mM Tris-Cl, pH 7.5, 500 mM NaCl, 5% glycerol, 5 mM imidazole...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/16/2015
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL