BDBM143247 US8940771, 59
SMILES Cc1nc(NC(=O)N2CC(F)(F)C[C@H]2C(N)=O)sc1-c1ccnc(c1)C1(C)CC1
InChI Key InChIKey=RZRTVDJHTRHMMH-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 143247
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 71nMpH: 7.5Assay Description:Typically frozen cells from 10 L of Tn5 cell culture were resuspended in Lysis Buffer 20 mM Tris-Cl, pH 7.5, 500 mM NaCl, 5% glycerol, 5 mM imidazole...More data for this Ligand-Target Pair
