BDBM143235 US8940771, 253::US8940771, 47
SMILES Cc1nc(NC(=O)N2CCC[C@@]2(C)C(N)=O)sc1-c1ccnc(c1)C(C)(C)C(F)(F)F
InChI Key InChIKey=RUXMYKHZCFYBBJ-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 143235
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 40nMpH: 7.5Assay Description:Typically frozen cells from 10 L of Tn5 cell culture were resuspended in Lysis Buffer 20 mM Tris-Cl, pH 7.5, 500 mM NaCl, 5% glycerol, 5 mM imidazole...More data for this Ligand-Target Pair
