BDBM14305 benzthiazole analog 8::benzyl N-[(2S)-1-(1,3-benzothiazol-2-yl)-3-(6-chloropyridin-3-yl)-1-oxopropan-2-yl]carbamate

SMILES Clc1ccc(C[C@H](NC(=O)OCc2ccccc2)C(=O)c2nc3ccccc3s2)cn1

InChI Key InChIKey=GULKMNFAKQJWAJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 14305   

TargetTryptase beta-2(Human)
Celera

LigandPNGBDBM14305(benzyl N-[(2S)-1-(1,3-benzothiazol-2-yl)-3-(6-chlo...)
Affinity DataKi: >1.50E+5nM ΔG°: >-5.16kcal/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed
TargetSerine protease 1(Bovine)
Celera

LigandPNGBDBM14305(benzyl N-[(2S)-1-(1,3-benzothiazol-2-yl)-3-(6-chlo...)
Affinity DataKi: >1.50E+5nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2007
Entry Details Article
PubMed