BDBM142739 US8937095, 1

SMILES CCNC(=O)C#Cc1ccc2\C(=C(\Nc3ccc(cc3)N3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=RVWWKXMUCMOEQG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142739   

TargetAurora kinase B-B(African clawed frog)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142739(US8937095, 1)
Affinity DataIC50: 2nMpH: 7.6Assay Description:The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
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TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM142739(US8937095, 1)
Affinity DataIC50: 10nMpH: 7.6Assay Description:The ATP-KM value of the complex is 61 uM. The kinase assays are run in the presence of 100 uM ATP using 10 uM of a substrate peptide. pAUB-IN847 was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent