BDBM142686 US8937068, 179

SMILES CCNC(=O)Nc1ccc2ncc(Nc3cnc4ccccc4c3)nc2n1

InChI Key InChIKey=GTXHPXZGOMSYCS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142686   

TargetMitogen-activated protein kinase 1(Human)
Zentaris

US Patent
LigandPNGBDBM142686(US8937068, 179)
Affinity DataIC50: 8.00E+3nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

LigandPNGBDBM142686(US8937068, 179)
Affinity DataIC50: 202nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Zentaris

US Patent
LigandPNGBDBM142686(US8937068, 179)
Affinity DataIC50: 1.40E+3nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8/9(Human)
Zentaris

US Patent
LigandPNGBDBM142686(US8937068, 179)
Affinity DataIC50: 8.10E+3nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent