BDBM142680 US8937068, 170

SMILES CCNC(=O)Nc1ccc2ncc(nc2n1)-c1ccc(O)cc1Cl

InChI Key InChIKey=MWVGADULZNNNBD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 142680   

TargetMitogen-activated protein kinase 1(Human)
Zentaris

US Patent
LigandPNGBDBM142680(US8937068, 170)
Affinity DataIC50: 103nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

LigandPNGBDBM142680(US8937068, 170)
Affinity DataIC50: 2.40E+3nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 14(Human)
Zentaris

US Patent
LigandPNGBDBM142680(US8937068, 170)
Affinity DataIC50: 3.16E+4nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 8/9(Human)
Zentaris

US Patent
LigandPNGBDBM142680(US8937068, 170)
Affinity DataIC50: 1.10E+3nMAssay Description:The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent