BDBM142565 US8933224, 158

SMILES Cc1nc([C@@H]2CCOC2)c2c(ncnn12)N1CCc2c(O)nc(nc2C1)C1CCCC1

InChI Key InChIKey=ROFYOKMWWVNPDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142565   

LigandPNGBDBM142565(US8933224, 158)
Affinity DataIC50: 0.227nMpH: 7.5Assay Description:The ability of a compound to inhibit PDE10 enzymatic activity can be demonstrated by any number of assays that are known in the art. The products of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2015
Entry Details
Go to US Patent