BDBM142414 US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-imidazol-4-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrazine

SMILES Cc1cnc(C)c2nc(CCc3c[nH]c(n3)-c3cccs3)nn12

InChI Key InChIKey=MQTYGQLGNQWMJT-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142414   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
H. Lundbeck

US Patent

LigandBDBM142414(US8927738, 5,8-Dimethyl-2-[2-(2-thiophen-2-yl-1H-i...)Copy SMILESCopy InChI

Affinity DataIC50: 0.400nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/1/2015
Entry Details
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