BDBM142400 US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-phenyl-1H-imidazol-4-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrazine

SMILES Cc1cnc(C)c2nc(CCc3cn(C)c(n3)-c3ccccc3)nn12

InChI Key InChIKey=TYMAPVBUEIBNMJ-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142400   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
H. Lundbeck

US Patent

LigandBDBM142400(US8927738, 5,8-Dimethyl-2-[2-(1-methyl-2-phenyl-1H...)Copy SMILESCopy InChI

Affinity DataIC50: 45nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
6/1/2015
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL