BDBM142266 US8933099, 102::US8933099, 32

SMILES CCOCCOc1cc2n(ccc2cc1Oc1ccnc(NC(=O)c2ccc(cc2)C2CN(C)C2)c1)C(=O)NC

InChI Key InChIKey=ROYMPAYADCOZNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 142266   

TargetFibroblast growth factor receptor 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM142266(US8933099, 102 | US8933099, 32)
Affinity DataIC50: 10.9nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

TargetFibroblast growth factor receptor 1(Human)
Eisai R&D Management

US Patent
LigandPNGBDBM142266(US8933099, 102 | US8933099, 32)
Affinity DataIC50: 6.5nMT: 2°CAssay Description:In this assay, the inhibitory activity of a test substance against the tyrosine kinase activity of FGFR1 protein is measured.To each well of a flat b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent