BDBM142038 US8927577, 117::US8927577, 19::US8927577, 32

SMILES Cc1cc2ccccc2nc1NC(C1CC(C)(C)C1)c1ccc(cc1)C(=O)NCCC(O)=O

InChI Key InChIKey=JHYVBNOMIUNRJS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 142038   

TargetPro-glucagon(Human)
Pfizer

US Patent
LigandPNGBDBM142038(US8927577, 117 | US8927577, 32 | US8927577, 19)
Affinity DataKi:  53nMpH: 7.4Assay Description:The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent

TargetGlucagon receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM142038(US8927577, 117 | US8927577, 32 | US8927577, 19)
Affinity DataKi:  53nMAssay Description:Displacement of [125I]-glucagon from human glucagon receptor expressed in Chem-1 cell membranes after 6 to 10 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2016
Entry Details Article
PubMed
TargetPro-glucagon(Human)
Pfizer

US Patent
LigandPNGBDBM142038(US8927577, 117 | US8927577, 32 | US8927577, 19)
Affinity DataKi:  74nMpH: 7.4Assay Description:The Glucagon SPA assay is used to determine the ability of test compounds to block the binding of glucagon-cex to the glucagon receptor. Test compoun...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2015
Entry Details
Go to US Patent