BDBM142018 US8927539, 10

SMILES CC(C)(O)CC1(CCN(C(=O)O1)C(C)(C)c1ccc(cc1)-c1ccn(C2CC2)c(=O)c1)c1ccccc1

InChI Key InChIKey=IHFKVAIBKDVABV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142018   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142018(US8927539, 10)
Affinity DataIC50: 38nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent