BDBM142010 US8927539, 3

SMILES CC(=C)CC1(CCN(C(=O)O1)C(C)(C)C#Cc1ccc2n(C)c(=O)ccc2c1)c1ccccc1

InChI Key InChIKey=CDCBSFVLVTUBBD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 142010   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM142010(US8927539, 3)
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:The inhibition of a microsomal preparation of 11beta -HSD1 by compounds of the invention was measured essentially as previously described (K. Solly, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2015
Entry Details
US Patent