BDBM1416 8-Amino-9b-phenyl-2,3-dihydrothiazolo[2,3-a]isoindol-5(9bH)-one::8-amino-9b-phenyl-2H,3H,5H,9bH-isoindolo[1,2-b][1,3]thiazol-5-one::Thiazoloisoindol-5-one deriv. 57

SMILES Nc1ccc2C(=O)N3CCSC3(c2c1)c1ccccc1

InChI Key InChIKey=XQDYHKPBFXMTHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1416   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Boehringer Mannheim

LigandPNGBDBM1416(8-amino-9b-phenyl-2H,3H,5H,9bH-isoindolo[1,2-b][1,...)
Affinity DataIC50: 4.50E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2004
Entry Details Article
PubMed