BDBM141523 US8921373, 8::US9365563, 200::US9878991, Compound 200

SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)cc1

InChI Key InChIKey=QVLGIPKHJUDLMW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 141523   

LigandPNGBDBM141523(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Affinity DataIC50: 32nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

LigandPNGBDBM141523(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Affinity DataIC50: 136nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM141523(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Affinity DataIC50: 31.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM141523(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Affinity DataIC50: 136nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

LigandPNGBDBM141523(US8921373, 8 | US9365563, 200 | US9878991, Compoun...)
Affinity DataIC50: 31.8nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent