BDBM141514 US8921373, 2::US8921373, 7::US9365563, 201::US9878991, Compound 201

SMILES FC(F)(F)c1ccc(NC(=O)N2CCC(=CC2)c2ncccc2Cl)nc1

InChI Key InChIKey=NHQIAAQHUFFKHK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 141514   

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 185nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 185nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 131nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 185nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
Go to US Patent

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 131nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded in poly-D-lysine-coated 96-well clear-bottom black plates (50,000 cells/well) in growth med...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent

LigandPNGBDBM141514(US8921373, 7 | US8921373, 2 | US9365563, 201 | US9...)
Affinity DataIC50: 185nMpH: 7.4Assay Description:Two days prior to performing this assay, cells are seeded on poly-D-lysine-coated 96-well clear-bottom black plates (commercially available from Bect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2018
Entry Details
Go to US Patent