BDBM141341 US8916577, 5

SMILES COc1cc(ccc1Nc1ncc2CCCc3c(nn(C)c3-c2n1)C(=O)N[C@H](CN)c1ccccc1)C(=O)NC1CCN(C)CC1

InChI Key InChIKey=NAGOZOOVQLAGAY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141341   

TargetDual specificity protein kinase TTK(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141341(US8916577, 5)
Affinity DataIC50: 469nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-1(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141341(US8916577, 5)
Affinity DataIC50: 497nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

TargetSerine/threonine-protein kinase pim-2(Human)
Nerviano Medical Sciences

US Patent
LigandPNGBDBM141341(US8916577, 5)
Affinity DataIC50: 3.76E+3nMpH: 3.0Assay Description:The inhibitory activity of putative kinase inhibitors and the potency of selected compounds were determined using a trans-phosphorylation assay.Speci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent