BDBM141325 US8653304, Comparative Compound 1

SMILES COc1c(NC(=O)NC2Cc3ccccc3C2)cc(cc1C(O)C(F)(F)F)C(C)(C)C

InChI Key InChIKey=AMTBUTKCYVXVTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 141325   

TargetMitogen-activated protein kinase 14(Human)
Toray Industries

US Patent
LigandPNGBDBM141325(US8653304, Comparative Compound 1)
Affinity DataIC50: 117nMT: 2°CAssay Description:Using human p38 MAPK alpha , the p38 MAPK inhibitory activity of Compound (I) was studied by a method partially modified from the method described in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent