BDBM141102 US8653100, 138::US8653100, 168::US8653100, 43

SMILES Cn1cc(cn1)S(=O)(=O)NCCOc1ccc2CCNC(c2c1)C1(CC(F)(F)C1)c1ccc(Cl)cc1

InChI Key InChIKey=JIBSGMNEMKZSAA-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 141102   

LigandPNGBDBM141102(US8653100, 138 | US8653100, 168 | US8653100, 43)
Affinity DataIC50: 100nMAssay Description:[3H]-Glycine uptake into recombinant CHO cells expressing human GlyT1: Human GlyT1c expressing recombinant hGlyT1c_5_CHO cells were plated at 20,000 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

LigandPNGBDBM141102(US8653100, 138 | US8653100, 168 | US8653100, 43)
Affinity DataKi: <100nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent

LigandPNGBDBM141102(US8653100, 138 | US8653100, 168 | US8653100, 43)
Affinity DataKi: <1.00E+3nMpH: 7.5Assay Description:Radioligand binding to human GlyT1c transporter-expressing membranes was carried out as described in Mezler et al., Molecular Pharmacology 74:1705-17...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/18/2015
Entry Details
Go to US Patent