BDBM140589 US8912224, 18

SMILES Fc1cccc(c1)C1CCc2cc(Oc3ncc(s3)C(=O)NCc3ccncc3)ccc2O1

InChI Key InChIKey=SNOIEIPMQYGTKA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140589   

TargetSodium/calcium exchanger 1(Human)
Sanofi

US Patent
LigandPNGBDBM140589(US8912224, 18)
Affinity DataIC50: 200nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the calcium-sensitive dye Fluo-4. CHO cells expressing NCX1 were loade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent

TargetSodium/calcium exchanger 1(Human)
Sanofi

US Patent
LigandPNGBDBM140589(US8912224, 18)
Affinity DataIC50: 600nMAssay Description:The assay is based on the monitoring of intracellular Ca2+concentrations using the PBX Calcium Assay Kit from BD (Becton, Dickinson and Company) with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2015
Entry Details
Go to US Patent