BDBM13994 5-(3-{2-[3-hydroxy-2-(methoxycarbonyl)phenoxymethyl]cyclopropyl}phenyl)-1,2-oxazole-3-carboxylic acid::Isoxazole carboxylic acid analog 5

SMILES COC(=O)c1c(O)cccc1OCC1CC1c1cccc(c1)-c1cc(no1)C(O)=O

InChI Key InChIKey=XSCGTWVGLHSJGP-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13994   

LigandPNGBDBM13994(5-(3-{2-[3-hydroxy-2-(methoxycarbonyl)phenoxymethy...)
Affinity DataKi:  2.30E+4nM ΔG°:  -6.26kcal/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2007
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13994(5-(3-{2-[3-hydroxy-2-(methoxycarbonyl)phenoxymethy...)
Affinity DataKi:  2.51E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed