BDBM139227 US8883797, 9

SMILES OC(Cn1cnnc1)(c1ccc(F)cc1F)C(F)(F)c1ccc2cc(Br)ccc2n1

InChI Key InChIKey=ZMHFHDVAVPEGFF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 139227   

TargetCytochrome P450 2C9(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM139227(US8883797, 9)
Affinity DataIC50: 1.30E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 μM by serial dilution with DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent

TargetCytochrome P450 2C19(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM139227(US8883797, 9)
Affinity DataIC50: 1.20E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 μM by serial dilution with DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent

TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

US Patent
LigandPNGBDBM139227(US8883797, 9)
Affinity DataIC50: 1.10E+4nMAssay Description:Solutions of each test compound were separately prepared at concentrations of 20000, 6000, 2000, 600, 200, and 60 μM by serial dilution with DMS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent