BDBM139168 US8614213, 19.94

SMILES FC(F)(F)c1ccc(Cl)c(c1)C(=O)N[C@H]1CC[C@H](CNc2n[nH]cc2-c2ccccc2)CC1

InChI Key InChIKey=KWZXGEAMKADLBX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139168   

TargetCorticotropin-releasing factor receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM139168(US8614213, 19.94)
Affinity DataIC50: 59nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human recombinant CRF-1 or CRF-2a receptors (Chen et al., Proc Natl Acad Sci USA 90, 8967-897...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent