BDBM139152 US8614213, 19.63

SMILES Fc1cccc2[nH]nc(NC[C@H]3CC[C@@H](CC3)NC(=O)c3cc(ccc3Cl)C(F)(F)F)c12

InChI Key InChIKey=GRGKFMBHYZKZMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139152   

TargetCorticotropin-releasing factor receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM139152(US8614213, 19.63)
Affinity DataIC50: 17nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human recombinant CRF-1 or CRF-2a receptors (Chen et al., Proc Natl Acad Sci USA 90, 8967-897...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent