BDBM139143 US8614213, 19.26

SMILES Cc1cc(NC[C@H]2CC[C@@H](CC2)NC(=O)c2cc(ccc2Cl)C(F)(F)F)ncc1F

InChI Key InChIKey=GAPJLNVFWNJPPG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 139143   

TargetCorticotropin-releasing factor receptor 1(Human)
Novartis

US Patent
LigandPNGBDBM139143(US8614213, 19.26)
Affinity DataIC50: 13nMAssay Description:Chinese hamster ovary (CHO) cells expressing either the human recombinant CRF-1 or CRF-2a receptors (Chen et al., Proc Natl Acad Sci USA 90, 8967-897...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent