BDBM13903 ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo[1,2-a][1,2,4]triazine-6-carboxylate::pyrrolo[2,1-f][1,2,4]triazine analog 5d

SMILES CCOC(=O)c1cn2ncnc(N[C@H](C)c3ccccc3)c2c1CC

InChI Key InChIKey=IKFNDVGENZZACI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13903   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13903(ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory concentration against Sal2 (salivary gland carcinoma) cell line expressing active HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM13903(ethyl 5-ethyl-4-{[(1R)-1-phenylethyl]amino}pyrrolo...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration against Sal2 (salivary gland carcinoma) cell line expressing active HER2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed