BDBM138800 US8877741, 2.126

SMILES C[C@H](NC(=O)c1cnco1)c1ccc(OC2CCN(C2)c2ccnc(N3CCC(F)(F)C3)c2F)cc1

InChI Key InChIKey=GGCOIONPJMLFEE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138800   

TargetAcetyl-CoA carboxylase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138800(US8877741, 2.126)
Affinity DataIC50: 45nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent