BDBM138767 US8877741, 2.93

SMILES C[C@H](NC(=O)c1cn[nH]c1)c1ccc(OC2CCN(C2)c2ccc(OC[C@H]3CC3(F)F)cn2)cc1

InChI Key InChIKey=AGZRDPDZMSBSMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138767   

TargetAcetyl-CoA carboxylase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138767(US8877741, 2.93)
Affinity DataIC50: 40nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent