BDBM138749 US8877741, 2.75

SMILES COCC(=O)Nc1nc(C)c(s1)C(=O)N[C@@H](C)c1ccc(OC2CCN(C2)c2ccnc(OCC3CC3)c2)cc1

InChI Key InChIKey=UOYDQDTVADFIRV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 138749   

TargetAcetyl-CoA carboxylase 2(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM138749(US8877741, 2.75)
Affinity DataIC50: 39nMpH: 7.5Assay Description:Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2015
Entry Details
Go to US Patent