BDBM13865 3-amidinobenzylindole carboxamide 49::5-amino-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-indole-2-carboxamide::CHEMBL307201

SMILES NC(=N)c1cccc(CNC(=O)c2cc3cc(N)ccc3n2Cc2cccc(c2)C(N)=N)c1

InChI Key InChIKey=IXDNONYWPHTGPP-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 13865   

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13865(5-amino-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-...)
Affinity DataKi:  51nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13865(5-amino-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-...)
Affinity DataKi:  84nMAssay Description:Inhibitory activity against serine protease factor Xa (fXa) was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13865(5-amino-N,1-bis[(3-carbamimidoylphenyl)methyl]-1H-...)
Affinity DataKi:  9.90E+3nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2007
Entry Details Article
PubMed