BDBM138387 US8877791, D1

SMILES OC(=O)CN1C(=S)S\C(=C/c2ccc(OC(=O)c3ccccc3I)cc2)C1=O

InChI Key InChIKey=RYIHRMGNQOGLPJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138387   

TargetPyruvate kinase PKM(Human)
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138387(US8877791, D1)
Affinity DataIC50: 2.00E+4nMAssay Description:Primary screening was performed using PKM2 in the presence of FBP. Compounds were chosen as potential "hits" if the compound demonstrated inhibition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetPyruvate kinase PKM(Human)
Beth Israel Deaconess Medical Center

US Patent
LigandPNGBDBM138387(US8877791, D1)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PKM2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details Article
PubMed