BDBM138280 US8871738, 63

SMILES COc1ncc(cc1-c1ccc(cc1[C@@H]1CC[C@H]2[C@H](OC(=O)N12)c1cc(F)cc(c1)C(F)(F)F)C(F)(F)F)-c1ccc(cc1C)C(O)=O

InChI Key InChIKey=ZOAPJFRUAASJIX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138280   

TargetCholesteryl ester transfer protein(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM138280(US8871738, 63)
Affinity DataIC50: 136nMpH: 7.4 T: 2°CAssay Description:First, low density lipoprotein (LDL) (Meridian) was biotinylated by incubating LDL with biotin for 1 hour on ice, after which it was dialyzed to remo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetCytochrome P450 2C8(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM138280(US8871738, 63)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed