BDBM138218 US8871778, 254

SMILES C[C@@H]1C[C@@H](O)CN1Cc1cn(nc1C)-c1ccnc(Nc2ccc3n(C)c(C)c(Cl)c3c2)n1

InChI Key InChIKey=GCGAGXWTXGPHLP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 138218   

TargetTyrosine-protein kinase SYK(Human)
Genosco

US Patent
LigandPNGBDBM138218(US8871778, 254)
Affinity DataIC50: 10nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Genosco

US Patent
LigandPNGBDBM138218(US8871778, 254)
Affinity DataIC50: 4.27E+3nMT: 2°CAssay Description:Compounds of the invention were initially diluted to 10 mM in 100% DMSO (CALBIOCHEM) for storage and made into kinase buffer solution to create a com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2015
Entry Details
Go to US Patent