BDBM1379 9b-(2,3-dimethylphenyl)-2H,3H,5H,9bH-isoindolo[1,2-b][1,3]thiazol-5-one::Thiazoloisoindol-5-one deriv. 23

SMILES Cc1cccc(c1C)C12SCCN1C(=O)c1ccccc21

InChI Key InChIKey=JIJBFEBNENJWBJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1379   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Boehringer Mannheim

LigandPNGBDBM1379(9b-(2,3-dimethylphenyl)-2H,3H,5H,9bH-isoindolo[1,2...)
Affinity DataIC50: 1.65E+3nMpH: 7.7 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2004
Entry Details Article
PubMed