BDBM13774 (1R,3R,4S,7S)-N-(benzenesulfonyl)-4-[2-(2-chlorophenoxy)-2-methylpropanamido]adamantane-1-carboxamide::adamantane ether 28

SMILES CC(C)(Oc1ccccc1Cl)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(=O)NS(=O)(=O)c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13774   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandPNGBDBM13774((1R,3R,4S,7S)-N-(benzenesulfonyl)-4-[2-(2-chloroph...)
Affinity DataIC50: 500nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM13774((1R,3R,4S,7S)-N-(benzenesulfonyl)-4-[2-(2-chloroph...)
Affinity DataIC50: 1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed