BDBM13764 (1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropanamido]-N-{[4-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl}adamantane-1-carboxamide::adamantane ether 18

SMILES CC(C)(Oc1ccc(Cl)cc1)C(=O)N[C@H]1C2C[C@@H]3C[C@@H]1C[C@](C3)(C2)C(=O)NCc1ccc(cc1)-c1nnn[nH]1

InChI Key

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 13764   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandPNGBDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 16nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Abbott Laboratories

LigandPNGBDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 2.60E+4nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 18nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Mouse)
Abbott Laboratories

LigandPNGBDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 6.20E+3nMAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Abbott Laboratories

LigandPNGBDBM13764((1R,3R,4S,7S)-4-[2-(4-chlorophenoxy)-2-methylpropa...)
Affinity DataIC50: 15.8nMAssay Description:Inhibition of 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed