BDBM13752 2-(S)-Phenethylamine analog 15::2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5-(trifluoromethyl)-4,5-dihydro-1,3-thiazol-4-one::A 1:1 mixture of epimers at C-5

SMILES C[C@H](NC1=NC(=O)C(C)(S1)C(F)(F)F)c1ccccc1F

InChI Key InChIKey=KNHNFKZUNFPPQE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13752   

LigandPNGBDBM13752(2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-methyl-5...)
Affinity DataKi:  20nM ΔG°:  -10.4kcal/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
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Date in BDB:
2/12/2007
Entry Details Article
PubMed