BDBM13747 2-((S)-1-(2-chlorophenyl)ethylamino)-5-isopropyl-5-methylthiazol-4(5H)-one::2-(S)-Phenethylamine analog 9::2-{[(1S)-1-(2-chlorophenyl)ethyl]amino}-5-methyl-5-(propan-2-yl)-4,5-dihydro-1,3-thiazol-4-one

SMILES CC(C)C1(C)SC(N[C@@H](C)c2ccccc2Cl)=NC1=O

InChI Key InChIKey=PTGSITWZKIAZHO-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13747   

LigandPNGBDBM13747(2-((S)-1-(2-chlorophenyl)ethylamino)-5-isopropyl-5...)
Affinity DataKi:  8nM ΔG°:  -10.9kcal/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed