BDBM13741 2-Benzylamine analog 3::5-isopropyl-5-methyl-2-((S)-1-phenylethylamino)thiazol-4(5H)-one::5-methyl-2-{[(1S)-1-phenylethyl]amino}-5-(propan-2-yl)-4,5-dihydro-1,3-thiazol-4-one

SMILES CC(C)C1(C)SC(N[C@@H](C)c2ccccc2)=NC1=O

InChI Key InChIKey=LESGKWOTXMFHMB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13741   

LigandPNGBDBM13741(5-isopropyl-5-methyl-2-((S)-1-phenylethylamino)thi...)
Affinity DataKi:  50nM ΔG°:  -9.85kcal/molepH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human or mouse11beta-HSD1. The fractional conversion of cortisone to cortisol was used to det...More data for this Ligand-Target Pair
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Date in BDB:
2/12/2007
Entry Details Article
PubMed