BDBM13656 3-Oxybenzamide 42::3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{[1-(pyridin-4-yl)piperidin-4-yl]methyl}benzamide

SMILES COc1cc(cc(OCCc2ccc(Cl)cc2Cl)c1OC)C(=O)NCC1CCN(CC1)c1ccncc1

InChI Key InChIKey=BUHZALANBOOLCL-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 13656   

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13656(3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{...)
Affinity DataKi:  50nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13656(3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{...)
Affinity DataKi:  50nMAssay Description:Inhibitory activity against human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/12/2014
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13656(3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human factor 10a using S-2765 as substrate preincubated for 15 mins followed by substrate addition measured between 1 and 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProthrombin(Human)
Aventis Pharma Deutschland

LigandPNGBDBM13656(3-[2-(2,4-dichlorophenyl)ethoxy]-4,5-dimethoxy-N-{...)
Affinity DataKi:  4.12E+3nMAssay Description:The inhibitory effect of test compound for human thrombin was determined by using the chromogenic substrates S-2366. The hydrolysis rates of chromoge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2007
Entry Details Article
PubMed