BDBM136295 US8853212, DDP-4 Inhibitor 11

SMILES N[C@H]1C[C@H](CSC1c1cc(F)ccc1F)N1Cc2n[nH]c(C#N)c2C1

InChI Key InChIKey=KQKASRAGSVKXIR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 136295   

TargetDipeptidyl peptidase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM136295(US8853212, DDP-4 Inhibitor 11)
Affinity DataIC50: 0.460nMpH: 7.5Assay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2015
Entry Details
Go to US Patent